Products Description

 

Product name

Losartan-H

Composition

 

Each tablet contains :

Losartan Potassium ... 50 mg

Hydrochlorothiazide .... 12.5 mg

 

 Indications

 

Hypertension.

 

Dosage & Administration

 

Losartan-H is administrated orally with or without food.

Oral Dosage :

Adults : initially, 50/12.5 mg PO once daily. Dosage range is
50/12.5-100/25 mg/day PO administered daily, or as directed by physician.

Contraindications :

Breast-feeding, pregnancy, children and sever hepatic impairment.

Cautions :

- In heart-failure patient may cause oliguria and progressive azotemia.

- Hepatic diseases, patients with cirrhosis demonstrated significantly increased plasma concentrations compared to normal patients. Dosage adjustment in this population is recommended.

- Hypovolemia in these patients, lower doses are recommended (see dosage)

- In renal artery stenosis patient may cause oliguria and progressive azotemia.

- Hydrochlorothiazide and related diuretics may exacerbate diabetes, gout and systemic lupus erythematosus. Electrolytes should be monitored particularly with high doses, long-term use, or in renal impairment. Hydrochlorothiazide and related diuretics should also be used with caution in nephrotic syndrome, hyperaldosteronism, malnourishment.

 Drug interaction :

Losartan has no specific interaction information.

Losartan belongs to Angiotensin II receptor antagonists and will have the following interactions :

Potassium salts, lithium, potassium sparing, diuretics, cyclosporine, alcohol, baclofen, clonidine, heparine, levodopa, methyldopa, minoxidil, anxiolytics and hypnotics .. etc.

Hydrochlorothiazide has the following drug interactions :

Alcohol, barbithurates, oral anti-diabetics agent, cholestyramine, corticosteroids, tubocurarine, amantadine, colestipol, diazoxide, digoxin, lithium, NSAIDs.

 

Presentation

 

Pack containing 3 blisters, each of 10 tablets.

 

 

Copyright 2008 biopharm-ye. All rights reserved