- is
taken one tablet per day, the dose may be increased to 3-4 tablets divided
dose/day as recommended by the physician, as following :
* 1
intake per day at breakfast if the dosage is 1 tablet daily.
* 2
intake per day at breakfast and at dinner if the dosage is 2 or 4 tablets daily.
* 3
intake per day at breakfast, at lunch and at dinner if the dosage 3 tablets
daily.
Contraindications :
- is
contraindicated in :
*
Hypersensitivity to sulfonylurea or biguanid.
*
Insulin
dependent type I.
*
Loss of
diabetes control with ketoacidosis.
*
Hypoglycemia due to not eating carbohydrate enough, prolong exercise or certain
adrenal and pituitary disorders.
Precautions
:
is used
with caution in :
*
Renal
and hepatic impairment.
*
Lactic
acidosis.
*
Heart
failure or recent myocardial infarction.
*
Severe
infection (respiratory tract infection & urinary tract infection).
*
After
radiological examine with iodinated contrast material for 2 days.
Drug
interactions :
-
effects is changed if concomitantly administered with
β.
blockers, estrogens,
corticosteroids, MAOI, calcium channel blockers, diuretics, oral contraceptives,
miconazole.
Side
effect :
- has
side effects like :
*
Hypoglycemia (tremor, blurred vision, sweating, palpitation).
*
Rarely
nausea, vomiting, diarrhea.
*
Skin
reactions (urticaria, itching).
Instructions
to the patients :
-
Swallow the tablets as whole with a drink of water.
- Take
the tablets with food at regular interval.
- Tell
your doctor about other medicines you are taking including non prescription
drugs.
- Tell
your doctor about any other diseases you have and the side effects appear
from .
- If you
forget to take the next dose at the usual time don't double the dose.
- Visit
your doctor for regular checks, learn how to monitor blood or urine sugars and
urine
ketones regularly , don't skip meals. If you are exercising much more than usual
you may need extra snacks to avoid hypoglycemic side effects. If you have mild
symptoms of low blood sugar, eat or drink sugars, it is important for you and
your family to recognize of hypo & hyperglycemia to reach your glycemic control
and to avoid their serious side effects.
Use
in pregnancy and lactation.
- not
recommended for use in pregnancy and lactation woman.
