- Skeletal muscle spasms, e.g. joint and muscle severe spasm due to inflammation or local trauma.

- Sedation in intensive care units, e.g. myocardial infarction (as an emergency therapy).

- Anesthesia for minor surgical procedures and gynecologic operations (as an adjunct agent).

- Psychoneurotic disorders characterized by tension, excitement, unrest, sleep disturbances, irritability, aggressiveness, reactive mood disturbances and somatic manifestations such as tense muscles, tremors and tachycardia.

- Stressful therapeutic or diagnostic interventions, e.g. endoscopy, some radiological procedures, biopsies, cardiac catheterization and cardioversion.

- Severe anxiety : up to 10 mg is given by i.m. or i.v., repeated if necessary after 4 hours.

- Premedication : 100 – 200 µg/ kg i.v.

- Seizures : 10 – 20 mg at a rate of 5 mg/min. repeated if necessary after 30-60 minutes. Once seizures have been controlled 3 mg/ kg may be given by slow i.v. over 24 hrs.

        * Children : 200 – 300 µg/ kg, or 1 mg may be given for each year of age.

- Muscle spasm : 10 mg i.m. or slow i.v., repeated if necessary after 4 hrs.

        * Tetanus (adults & children) : 100 – 300 µg/ kg every 4 hours by slow continuous i.v. infusion.

- Alcohol withdrawal syndrome : in severe symptoms 10 mg i.m. or i.v.