Administration should be given under supervision
of the physician. As a general rule the course
of treatment should be limited to 7-10 days.
Adults :
Intramuscular administration 80 mg twice a day.
This dosage may be increased although it is
generally sufficient in urogenital infections.
In case of burns and systemic infections
depending on its seriousness, during the acute
phase initially administer 80 mg Biogent
by i.m. route 3 times daily. Afterwards the dose
is reduced to 40 mg gentamicin 3 times daily.
In meningitis and encephalitis the dose should
be 80 mg 4 times daily.
In cases where life is in danger owing to the
severity of the infections the total daily
dosage may be increased to 5 mg/kg of body
weight but vestibular and kidney function must
be watched.
Infants & Children : The doses are usually somewhat higher than those in adults but
exact dosage recommendations vary. The suggested
dose is 3 mg of gentamicin / kg every 12 hours
in premature infants & those up to 2 weeks of
age, with older neonates & children receiving 2
mg / kg every 8 hours. Alternatively, 2.5 mg/ kg
every 12 hours in the first week of life; 2.5 mg
/ kg every 8 hours in infants & neonates; and
2-2.5 mg / kg every 8 hours in children has been
suggested.
